Gene information
Official symbol ACE2
Official full name angiotensin I converting enzyme 2
Gene type protein-coding gene
ChromosomeXp22.2
Resources
Entrez Gene 59272
HGNC HGNC:13557
Ensembl ENSG00000130234
Vega OTTHUMG00000021177
UCSC uc004cxb.2
GO terms: 64 records
GO Description Category LogP Number of genes Detail
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003073 regulation of systemic arterial blood pressure GO Biological Processes -22.2238525 34 More
GO:0004175 endopeptidase activity GO Molecular Functions -25.2809598 44 More
GO:0005788 endoplasmic reticulum lumen GO Cellular Components -47.2996164 57 More
GO:0005903 brush border GO Cellular Components -3.40315955 7 More
GO:0006518 peptide metabolic process GO Biological Processes -2.74792434 15 More
GO:0006865 amino acid transport GO Biological Processes -1.31617538 4 More
GO:0006897 endocytosis GO Biological Processes -8.07395492 24 More
GO:0006937 regulation of muscle contraction GO Biological Processes -20.8046481 43 More
GO:0006942 regulation of striated muscle contraction GO Biological Processes -11.0877013 23 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0007631 feeding behavior GO Biological Processes -8.63374021 12 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0008233 peptidase activity GO Molecular Functions -21.0463733 46 More
GO:0008237 metallopeptidase activity GO Molecular Functions -10.3008607 18 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0010469 regulation of signaling receptor activity GO Biological Processes -13.5880476 20 More
GO:0015849 organic acid transport GO Biological Processes -6.14345140 15 More
GO:0016324 apical plasma membrane GO Cellular Components -4.50542891 15 More
GO:0016485 protein processing GO Biological Processes -23.0561441 30 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0031253 cell projection membrane GO Cellular Components -3.08510132 12 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031526 brush border membrane GO Cellular Components -3.31231720 5 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034767 positive regulation of ion transmembrane transport GO Biological Processes -11.2867591 18 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043409 negative regulation of MAPK cascade GO Biological Processes -13.5471736 35 More
GO:0043603 cellular amide metabolic process GO Biological Processes -1.84597279 17 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044070 regulation of anion transport GO Biological Processes -12.6410846 24 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045177 apical part of cell GO Cellular Components -8.17813885 46 More
GO:0045823 positive regulation of heart contraction GO Biological Processes -10.6953794 15 More
GO:0045933 positive regulation of muscle contraction GO Biological Processes -10.2635447 16 More
GO:0045989 positive regulation of striated muscle contraction GO Biological Processes -6.22004109 7 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048662 negative regulation of smooth muscle cell proliferation GO Biological Processes -21.7509412 30 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0051604 protein maturation GO Biological Processes -20.0856790 31 More
GO:0051701 biological process involved in interaction with host GO Biological Processes -10.6054189 28 More
GO:0055117 regulation of cardiac muscle contraction GO Biological Processes -9.51337974 19 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:0098862 cluster of actin-based cell projections GO Cellular Components -2.30896381 7 More
GO:1901888 regulation of cell junction assembly GO Biological Processes -8.71146171 30 More
GO:1901890 positive regulation of cell junction assembly GO Biological Processes -5.75086352 17 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1903524 positive regulation of blood circulation GO Biological Processes -11.6803256 16 More
GO:1903779 regulation of cardiac conduction GO Biological Processes -5.87603013 9 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904064 positive regulation of cation transmembrane transport GO Biological Processes -10.8655330 17 More
GO:2000272 negative regulation of signaling receptor activity GO Biological Processes -7.12747015 9 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04974 Protein digestion and absorption KEGG Pathway -4.19153592 8 More
hsa05171 Coronavirus disease - COVID-19 KEGG Pathway -24.8179886 34 More
Drug-Gene interaction
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Related drugs: 4 records
Related studies: 9 records
Molecular factor Omics type Application Objective MI type Reference
NG_012575.2:g.[7219A>G;14934G>A;22218C>G] genomics myocardial infarction[diagnosis] myocardial infarction Yang W et al. Clin Sci (Lond). 2006
angiotensin-converting enzyme 2 proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Ortiz-Perez JT et al. PLoS One. 2013
angiotensin-converting enzyme 2 proteomics left ventricular remodeling[prognosis (bad)] acute ST elevation myocardial infarction Ortiz-Perez JT et al. PLoS One. 2013
angiotensin-converting enzyme 2 proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Liu W et al. Cardiovasc Diabetol. 2013
angiotensin-converting enzyme 2 proteomics myocardial infarction[diagnosis] myocardial infarction Narula S et al. Lancet. 2020
NG_012575.2:g.22218C>G genomics myocardial infarction[diagnosis] myocardial infarction Yang W et al. Clin Sci (Lond). 2006
NG_012575.2:g.7219A>G genomics myocardial infarction[diagnosis] myocardial infarction Yang W et al. Clin Sci (Lond). 2006
angiotensin-converting enzyme 2 proteomics myocardial infarction[diagnosis] myocardial infarction Cambien F et al. Circulation. 1994
angiotensin-converting enzyme 2 proteomics prolonged hospital stay[prognosis (bad)] acute myocardial infarction El-Menyar AA et al. Coron Artery Dis. 2006
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